: Samuel Chukwueze equalized in the 57th minute, followed by an Arnaut Danjuma goal in the 70th minute to give Villarreal the lead.
On September 15, 2022, Villarreal traveled to Israel for a demanding midweek fixture. Villarreal vs Hapoel Be'er
: Tomer Hemed put the visitors ahead in the 48th minute after a handball by Aïssa Mandi led to a penalty. : Samuel Chukwueze equalized in the 57th minute,
The return leg on October 27, 2022, at the Estadio Ciudad de Valencia, proved even more unpredictable. at the Estadio Ciudad de Valencia
: Hapoel's Rotem Hatuel leveled the score in the 63rd minute, temporarily shifting the game's momentum.