Grey's Anatomy — S16e16

Alex explains she will always be "his person," but he found a reason to stay away that he couldn't ignore.

He expresses his gratitude for their mentorship over the years. The Big Reveal: Izzie Stevens and the Twins Grey's Anatomy s16e16

He discovered that Izzie used the embryos they froze years ago when she had cancer. Alex explains she will always be "his person,"

Season 16, Episode 16 of Grey's Anatomy , titled serves as the official farewell to original cast member Justin Chambers , who played Dr. Alex Karev . The episode aired on March 5, 2020, and is one of the most controversial in the series' history due to how it handles Alex's departure. ✉️ The Core Format: Letters from Alex Season 16, Episode 16 of Grey's Anatomy ,

After reading the letter and realizing her marriage is over, Jo heads back to work, determined to stay strong despite the heartbreak. 🗣️ Fan and Critic Reaction

They make the life-altering decision to foster Joey , a teenager Bailey treated who had been living in the foster care system.