The most comprehensive and official resource for drug interactions at the "Contraindicated" (contre-indiqué) level in France is the , published by the Agence Nationale de Sécurité du Médicament (ANSM) .
: Absolute prohibition. The association must not be prescribed. The most comprehensive and official resource for drug
: Should be avoided unless a strict benefit/risk assessment justifies it. associations to be avoided (ASDEC)
: This is the primary reference guide used by healthcare professionals to identify absolute contraindications (CI), associations to be avoided (ASDEC), and precautions for use. The most comprehensive and official resource for drug
The ANSM classifies interactions into four increasing grades of importance:
