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Before the modern era, many cultures recognized and even revered people who did not fit the male-female binary:

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The modern LGBTQ+ rights movement was forged through resistance to police harassment and discrimination. Before the modern era, many cultures recognized and

"Two-Spirit" individuals, such as the Navajo nádleehi , held distinct social and spiritual roles. Before the modern era

In 1952, Christine Jorgensen became an international sensation as the first American to become widely known for undergoing sex reassignment surgery. The Activism Era (1960s – 1990s)