The study explores how COUP-TF , a member of the steroid/thyroid hormone receptor superfamily, acts as a "promiscuous" repressor. It can bind to various DNA response elements (A/GGGTCA repeats) and block the activity of other receptors like: Vitamin D3 receptor (VDR) Thyroid hormone receptor (TR) Retinoic acid receptor (RAR) Why the .rar format?
. Key Details of the Paper
Originally published in the Journal of Biological Chemistry (JBC). 53592.rar